M BERNARD UZZAN

Rhumatologue

RPPS 10001131209

📊 Reconnaissance scientifique : 29/100📝 100 articles publiés🇫🇷 Publications académiques françaises (2)

✨ Génération du profil synthétique IA en cours…

Activité de recherche & publications

Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.

Influence scientifique

29 articles ont été cités au moins 29fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis

Critical care medicine · 2006

📚 520 citations🎯 RCR 16.13Top 1% NIH

Microvessel density as a prognostic factor in women with breast cancer: a systematic review of the literature and meta-analysis

Cancer research · 2004

📚 397 citations🎯 RCR 8.82Top 3% NIH

Lire l'abstract Crossref ↓

Abstract We performed a meta-analysis of all 87 published studies linking intratumoral microvessel density (MVD), reflecting angiogenesis, to relapse-free survival (RFS) and overall survival (OS). With median MVD as cutoff, MVD impact was measured by risk ratio (RR) between the two survival distributions. Seventeen studies did not mention survival data or fit inclusion criteria. Twenty-two were multiple publications of the same series, leaving 43 independent studies (8936 patients). MVD was assessed by immunohistochemistry, using antibodies against factor VIII (27 studies; n = 5262), CD31 (10 studies; n = 2296), or CD34 (8 studies; n = 1726). MVD might be a better prognostic factor when assessed by CD31 or CD34 versus factor VIII (P = 0.11). For RFS, statistical calculations were performed in 25 studies (6501 patients). High MVD significantly predicted poor survival [RR = 1.54 for RFS and OS with the same 95% confidence interval (CI), 1.29–1.84]. Twenty-two studies analyzed separately lymph node-negative patients (n = 3580), for whom predictors of poor survival are requested. This latter meta-analysis included 15 studies for RFS (2727 patients) and 11 for OS (1926 patients). High MVD significantly predicted poor survival [RR = 1.99 for RFS (95% CI, 1.33–2.98) and RR = 1.54 for OS (95% CI, 1.01–2.33)]. Between-study variations could result from patient selection criteria, techniques to stain and count microvessels, and cutoff selection. MVD was a significant although weak prognostic factor in women with breast cancer. Standardization of MVD assessment is needed.

Effects on bone mass of long term treatment with thyroid hormones: a meta-analysis

The Journal of clinical endocrinology and metabolism · 1996

📚 263 citations🎯 RCR 9.43Top 3% NIH🔓 Open Access📄 PDF gratuit ↗

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M BERNARD UZZAN

Pourquoi vous devez consulter ce praticien

Activité de recherche & publications

Publications académiques en France

Lieu de consultation

Tarifs & secteur de conventionnement

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Top publications · les plus citées

Publications scientifiques (19) — classées par pathologie

Revue / méta-analyse13

Revue générale5

Essai clinique3

Gériatrie3

Activité physique / Rééducation1

Pharmacovigilance1

Sjögren1

Transversal1

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