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Auteur de référence en rhumatologie
32 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
86.1 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR VALERIE SCHMID-GALLON
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Health science reports · 2024
AbstractBackgroundIn this study, we investigated whether the association of curcumin and docetaxel among advanced and metastatic breast cancer patients in first or second‐line treatment potentiated the objective response rate.Patients/MethodsA multicentre, randomized, open label, phase‐II study was conducted and included 42 patients from July 2009 to January 2017. The primary endpoint was the objective response rate of the docetaxel‐curcumin combination in comparison with docetaxel alone. The secondary endpoints were the assessment of clinical benefit, overall survival, time‐to‐progression, progression‐free survival, compliance, and safety. An interim analysis was planned to evaluate safety and efficacy.ResultsIn this interim analysis conducted on 37 patients (19 in the control group vs. 18 in the experimental group), no difference was observed for the objective response rate (p = 0.25, control 73.7% vs. experimental 55.6%). Concerning clinical benefit, overall survival and time‐to‐progression, we also failed to show any difference between the two arms. A slight tendency towards longer progression‐free survival at 12 months after randomization was observed in the curcumin group (65.5% vs. 41.4%) but this difference did not reach significance (p = 0.14).ConclusionIn this study, we showed for the first time that adding oral curcumin for advanced and metastatic breast cancer patients treated with first or second‐line docetaxel was not efficacious, although safe. Consequently, this study was stopped for reasons of futility. Further studies with a larger number of patients, a different curcumin preparation, a longer treatment period and a pharmacokinetic evaluation of curcumin are needed to explore the real efficacy of this compound.
ArXiv · 2024
JMIR medical education · 2024
Large-scale medical data sets are vital for hands-on education in health data science but are often inaccessible due to privacy concerns. Addressing this gap, we developed the Health Gym project, a free and open-source platform designed to generate synthetic health data sets applicable to various areas of data science education, including machine learning, data visualization, and traditional statistical models. Initially, we generated 3 synthetic data sets for sepsis, acute hypotension, and antiretroviral therapy for HIV infection. This paper discusses the educational applications of Health Gym’s synthetic data sets. We illustrate this through their use in postgraduate health data science courses delivered by the University of New South Wales, Australia, and a Datathon event, involving academics, students, clinicians, and local health district professionals. We also include adaptable worked examples using our synthetic data sets, designed to enrich hands-on tutorial and workshop experiences. Although we highlight the potential of these data sets in advancing data science education and health care artificial intelligence, we also emphasize the need for continued research into the inherent limitations of synthetic data.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace · 2026 · Journal Article
Akhil A, Joseph JR, Puttegowda VD, V M, et al.
Cureus · 2025 · Case Reports
Parthasarathy I, V GK, Hussain SA
Bioinformation · 2025 · Journal Article
G N, M SSL, V S, K S, et al.
Disability and rehabilitation · 2025 · Journal Article
Patel H, Shah S, V P
Biomedical physics & engineering express · 2025 · Journal Article
D K, D P, P V, G A, et al.
ArXiv · 2024 · Journal Article
Moawad AW, Janas A, Baid U, Ramakrishnan D, et al.
Nature communications · 2024 · Journal Article
Valerie NCK, Sanjiv K, Mortusewicz O, Zhang SM, et al.
JMIR medical education · 2024 · Journal Article
Kuo NI, Perez-Concha O, Hanly M, Mnatzaganian E, et al.
ACG case reports journal · 2023 · Case Reports
Zampaglione L, Rougemont AL, Rubbia-Brandt L, Abramowicz M, et al.
Interventional pain medicine · 2023 · Journal Article
Gautam S, Gopal VG, Khuba S, Agarwal A, et al.
Health economics review · 2025 · Journal Article
Shobha V, Singhai S, Haridas V, V S, et al.
International journal of surgery case reports · 2025 · Case Reports
Noémie VH, Catherine V, Laure M, Stephen T, et al.
Radiology case reports · 2024 · Case Reports
Simargi Y, Dewi AP, Charlee MA, Valerie N, et al.
International orthopaedics · 2024 · Letter
Cureus · 2024 · Journal Article
Varaganti V, Vadakedath S, Ca J, Kandi V, et al.
Lupus · 2024 · Journal Article
Shobha V, Preet Singh Y, Malviya S, Ponniah Subramanian AR, et al.
Cureus · 2024 · Case Reports
V K, Srinivas A, T A V, Jayaprakash V, et al.
Lupus · 2024 · Journal Article
Shobha V, Rajasekhar L, Manuel S, V N, et al.
Advances in rehabilitation science and practice · 2025 · Case Reports
Wee SK, Valerie ZYN, Phua MW, Lui WL, et al.
International journal of surgery case reports · 2025 · Case Reports
Noémie VH, Catherine V, Laure M, Stephen T, et al.
Radiology case reports · 2024 · Case Reports
Simargi Y, Dewi AP, Charlee MA, Valerie N, et al.
Current pain and headache reports · 2025 · Journal Article
Hegde NC, Mishra A, V D, Maiti R, et al.
Health science reports · 2024 · Journal Article
Judith PJ, Maureen B, Mélanie P, Fabrice K, et al.
European journal of pediatrics · 2026 · Journal Article
Oswal JS, Bellary VS, Kadimisetty NB, Sarangi B, et al.
Neuropsychological rehabilitation · 2025 · Journal Article
Kirstin S, Matthias G, Valetin B, Valerie S, et al.
HIV medicine · 2026 · Journal Article
Bruno S, Olivier R, Valérie P, Paul L, et al.
Cureus · 2025 · Journal Article
Nallaperumal S, V P, M C V, Pusapati LCV, et al.
Current pain and headache reports · 2025 · Journal Article
Hegde NC, Mishra A, V D, Maiti R, et al.
International journal of surgery case reports · 2025 · Case Reports
Noémie VH, Catherine V, Laure M, Stephen T, et al.
Environmental toxicology and pharmacology · 2023 · Journal Article
Mathesh K, Manickam K, Mallord JW, Mahendran K, et al.
Ocular immunology and inflammation · 2023 · Case Reports
B Singh S, Kanakath AV, Saravanan V, K S J, et al.
The Journal of arthroplasty · 2026 · Journal Article
Ng MK, Mont MA, Afolabi M, V PN, et al.
European journal of pediatrics · 2026 · Journal Article
Oswal JS, Bellary VS, Kadimisetty NB, Sarangi B, et al.
npj aging · 2024 · Journal Article
Pemmasani SK, R G S, V S, Bhattacharyya R, et al.
Environmental toxicology and pharmacology · 2023 · Journal Article
Mathesh K, Manickam K, Mallord JW, Mahendran K, et al.
Studies in health technology and informatics · 2025 · Journal Article
Valerie IC, Holloway L, Churches T, Kennedy G
Annapareddy A, Mulpur P, Jayakumar T, Kikkuri RR, et al.
Cureus · 2023 · Journal Article
V K, Mani R, Venkatesh V, Kunhikannan S, et al.
International orthopaedics · 2023 · Journal Article
Annapareddy A, Mulpur P, Jayakumar T, Kikkuri RR, et al.