📇 Rhumatologue ·

MME ELISABETH SAFRANA-SOUHAMI

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Auteur de référence en rhumatologie
25 articles scientifiques publiés — un praticien à la pointe de la recherche

Rhumatologue

RPPS 10000430701

✨ Génération du profil synthétique IA en cours…

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Top publications · les plus citées

Microalgae culture quality indicators: a review

Critical reviews in biotechnology · 2021

📚 50 citations🎯 RCR 5.29Top 7% NIH🔓 Open Access📄 PDF gratuit ↗

The use of a UV-C disinfection robot in the routine cleaning process: a field study in an Academic hospital

Antimicrobial resistance and infection control · 2021

📚 25 citations🎯 RCR 2.29Top 23% NIH🔓 Open Access📄 PDF gratuit ↗

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Abstract Background Environmental surface decontamination is a crucial tool to prevent the spread of infections in hospitals. However, manual cleaning and disinfection may be insufficient to eliminate pathogens from contaminated surfaces. Ultraviolet-C (UV-C) irradiation deploying autonomous disinfection devices, i.e. robots, are increasingly advertised to complement standard decontamination procedures with concurrent reduction of time and workload. Although the principle of UV-C based disinfection is proven, little is known about the operational details of UV-C disinfection delivered by robots. To explore the impact of a UV-C disinfection robot in the clinical setting, we investigated its usability and the effectiveness as an add-on to standard environmental cleaning and disinfection. Additionally, its effect on Candida auris, a yeast pathogen resistant to antifungals and disinfectants, was studied. Methods After setting the parameters “surface distance” and “exposure time” for each area as given by the manufacturer, the robot moved autonomously and emitted UV-C irradiation in the waiting areas of two hospital outpatient clinics after routine cleaning and/or disinfection. To quantify the efficacy of the robotic UV-C disinfection, we obtained cultures from defined sampling sites in these areas at baseline, after manual cleaning/disinfection and after the use of the robot. Four different C. auris strains at two concentrations and either in a lag or in a stationary growth phase were placed in these areas and exposed to UV-C disinfection as well. Results The UV-C irradiation significantly reduced the microbial growth on the surfaces after manual cleaning and disinfection. C. auris growth in the lag phase was inhibited by the UV-C irradiation but not in the presence of the rim shadows. The effects on C. auris in the stationary phase were differential, but overall C. auris strains were not effectively killed by the standard UV-C disinfection cycle. Regarding usability, the robot’s interface was not intuitive, requiring advanced technical knowledge or intensive training prior to its use. Additionally, the robot required interventions by the technical operator during the disinfection process, e.g. stopping due to unforeseen minor dislocation of items during the clinical service or due to moving individuals, making it a delicate high-tech device but not yet ready for the autonomous use in the clinical routine. Conclusions Presently, the UV-C robot tested in this study is not ready to be integrated in the environmental cleaning and disinfection procedures in our hospital. The single standard disinfection UV-C irradiation cycle is not sufficient to inactivate pathogens with augmented environmental resilience, e.g. C. auris, particularly when microbial loads are high.

Elevated markers of DNA damage and senescence are associated with the progression of albuminuria and restrictive lung disease in patients with type 2 diabetes

EBioMedicine · 2023

📚 15 citations🎯 RCR 1.98🔓 Open Access

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MME ELISABETH SAFRANA-SOUHAMI

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Lieu de consultation

Tarifs & secteur de conventionnement

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Top publications · les plus citées

Publications scientifiques (25) — classées par pathologie

Transversal17

Génétique2

Recommandations2

Santé mentale / fatigue2

Essai clinique1

Revue générale1

Risque cardio-vasculaire1

Vraie vie / RWE1

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