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Auteur de référence en rhumatologie
37 articles scientifiques publiés — un praticien à la pointe de la recherche
✨ Génération du profil synthétique IA en cours…
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The Annals of thoracic surgery · 2026
JAAD international · 2026
Blood advances · 2026
Abstract This real-world retrospective cohort study evaluated utilization and comparative effectiveness of covalent Bruton tyrosine kinase inhibitor (cBTKi) monotherapies in relapsed/refractory mantle cell lymphoma (R/R MCL) from electronic health records in the United States. Adults with R/R MCL who received second- or third-line (2L/3L) zanubrutinib, acalabrutinib, or ibrutinib monotherapy, on or after 1 January 2018, were included. Inverse probability of treatment weighting was used in adjusted Cox models to compare real-world time-to-next treatment (rwTTNT) and overall survival (rwOS). Among 698 patients who received 2L/3L cBTKi monotherapy, 49%, 32%, and 19% received acalabrutinib, ibrutinib, and zanubrutinib, respectively. Unadjusted analyses showed median rwTTNT for 2L zanubrutinib, acalabrutinib, and ibrutinib was 14.5 (95% confidence interval [CI], 11.0-23.2), 12.8 (95% CI, 10.5-15.6), and 10.3 (95% CI, 7.6-13.7) months, and median rwOS was 26.4 (95% CI, 23.2 to not reached [NR]), 29.2 (95% CI, 22.9-38.1), and 29.3 (95% CI, 21.8-41.6) months, respectively. Median rwTTNT for 3L zanubrutinib, acalabrutinib, and ibrutinib was 21.1 (95% CI, 3.9 to NR), 9.2 (95% CI, 6.8-14.7), and 9.6 (95% CI, 4.8-18.0) months, and median rwOS was NR (95% CI, 27.3 to NR), 27.4 (95% CI, 15.1-42.2), and 27.0 (95% CI, 15.6 to NR) months, respectively. Adjusted models in the 2L/3L cohorts combined showed numerically longer rwTTNT and statistically significantly longer rwOS for zanubrutinib vs ibrutinib (hazard ratio, 0.63; 95% CI, 0.42-0.96), and trends for improved rwTTNT and rwOS for zanubrutinib over acalabrutinib. Toxicity was a frequent reason for changing to another cBTKi. These findings suggest potential improvements in rwTTNT and rwOS with the use of second- and next-generation cBTKis for R/R MCL from 2018 and beyond.
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Data in brief · 2026 · Journal Article
Collewet G, Traore A, Leca A, Challois S, et al.
The journal of applied laboratory medicine · 2026 · Journal Article
Peck Palmer OM, Johnson-Davis KL, Yang HS, Pierre CC
The American journal of tropical medicine and hygiene · 2026 · Journal Article
Delcher C, Park C, Bae J, Pierre DM, et al.
Military medicine · 2026 · Journal Article
Pierre EF, Sanborn RM, Bailey A, Chin A, et al.
Angewandte Chemie (International ed. in English) · 2026 · Journal Article
Joaqui-Joaqui MA, Tran PN, Marlin A, Armstrong-Pavlik F, et al.
Intensive care medicine · 2026 · Journal Article
Preau S, Singer M, Pierre A
JAAD international · 2026 · Letter
Brenaut E, Ficheux AS, Pierre O, Taieb C, et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2026 · Journal Article
Dougniaux G, Sabot B, Lestaevel BD, Pierre S
Substance use & addiction journal · 2026 · Journal Article
Applewhite D, Regan S, Pierre W, Kennedy E, et al.
The American journal of sports medicine · 2026 · Journal Article
Johnstone T, Pierre K, Roh E, Fredericson M, et al.
Communications medicine · 2026 · Journal Article
Munhall AC, Eiwaz MB, Hebert JF, Groat T, et al.
The Annals of thoracic surgery · 2026 · Journal Article
Kitazawa S, Bernards N, Sata Y, Yokote F, et al.
Diabetes care · 2026 · Journal Article
Shah S, Hasenböhler A, Javaux G, Payen de la Garanderie M, et al.
American journal of obstetrics and gynecology · 2026 · Published Erratum
Gachon B, Durocher L, Garabedian C, Guerby P, et al.
The Journal of arthroplasty · 2026 · Journal Article
Kashir I, Shanthanna H, Khanna V, Mbuagbaw L, et al.
PLOS global public health · 2026 · Journal Article
Gad N, Tlhaloganyang BP, Habineza JC, Pierre NS, et al.
JTCVS open · 2026 · Journal Article
Nakahashi K, Sata Y, Ishiwata T, Inage T, et al.
American journal of physiology. Gastrointestinal and liver physiology · 2026 · Journal Article
Vieujean S, Atreya R, Buda A, Caradec J, et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026 · Journal Article
Yang AW, Pierre JJ, Lewis-Cruz JL, Pillion EM, et al.
Physical review letters · 2026 · Journal Article
Aprile E, Aalbers J, Abe K, Ahmed Maouloud S, et al.
American journal of physiology. Gastrointestinal and liver physiology · 2026 · Journal Article
Vieujean S, Atreya R, Buda A, Caradec J, et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026 · Journal Article
Yang AW, Pierre JJ, Lewis-Cruz JL, Pillion EM, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.
Haemophilia : the official journal of the World Federation of Hemophilia · 2026 · Journal Article
Sattler L, Herb A, Pierre L, Wimmer J, et al.
Thrombosis and haemostasis · 2026 · Journal Article
Fauchier L, Lochon L, Lenormand T, Pierre B, et al.
Blood advances · 2026 · Journal Article
Phillips T, Di M, Miller TA, Wang J, et al.
Circulation. Population health and outcomes · 2026 · Letter
Kamojjala S, Adhikari S, Meng Y, Sweeney G, et al.
The Pediatric infectious disease journal · 2026 · Journal Article
Agathis NT, Sato K, O'Connor S, Robaugh RIB, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.
European journal of preventive cardiology · 2026 · Journal Article
Ait-Oufella H, Marie-Cécile P, Muriel A, Guedon A, et al.
Environmental health : a global access science source · 2026 · Journal Article
Yan LD, Sufra R, St Sauveur R, Celestin K, et al.
Lancet (London, England) · 2026 · Journal Article
Colombo N, Zsiros E, Parma G, Rulli E, et al.
Ecology and evolution · 2026 · Journal Article
Veillat L, Cocquempot C, Streito JC, Pierre É, et al.
The Pediatric infectious disease journal · 2026 · Journal Article
Agathis NT, Sato K, O'Connor S, Robaugh RIB, et al.
European heart journal. Digital health · 2026 · Journal Article
Garcia R, Gras D, Mansourati J, Defaye P, et al.
Psychology and psychotherapy · 2026 · Journal Article
Rudenstine S, Pierre J, Schulder T, Goldberg P
European journal of epidemiology · 2026 · Journal Article
Shah S, Hasenböhler A, Javaux G, de la Garanderie MP, et al.
PloS one · 2026 · Journal Article
Anxionnat R, Bernard N, Mariet AS, Pujol S, et al.
The American journal of sports medicine · 2026 · Journal Article
Lencioni A, Raji Y, Pierre KJ, Aoki S, et al.
European heart journal. Digital health · 2026 · Journal Article
Garcia R, Gras D, Mansourati J, Defaye P, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.
Injury · 2026 · Journal Article
Stella O, Benjamin M, Hamid H, Pierre P, et al.
European journal of cancer (Oxford, England : 1990) · 2026 · Published Erratum
Salomé V, Antoine J, Côme L, Pierre G, et al.