MME NAJIBA LAHLOU

Rhumatologue

RPPS 10001377802

📊 Reconnaissance scientifique : 44/100📝 125 articles publiés🇫🇷 Publications académiques françaises (8)

✨ Génération du profil synthétique IA en cours…

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Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.

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44 articles ont été cités au moins 44fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.

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Top publications · les plus citées

Consensus statement on the use of gonadotropin-releasing hormone analogs in children

Pediatrics · 2009

📚 560 citations🎯 RCR 20.19Top 1% NIH🔓 Open Access📄 PDF gratuit ↗

Lire l'abstract Crossref ↓

OBJECTIVE. Gonadotropin-releasing hormone analogs revolutionized the treatment of central precocious puberty. However, questions remain regarding their optimal use in central precocious puberty and other conditions. The Lawson Wilkins Pediatric Endocrine Society and the European Society for Pediatric Endocrinology convened a consensus conference to review the clinical use of gonadotropin-releasing hormone analogs in children and adolescents.PARTICIPANTS. When selecting the 30 participants, consideration was given to equal representation from North America (United States and Canada) and Europe, an equal male/female ratio, and a balanced spectrum of professional seniority and expertise.EVIDENCE. Preference was given to articles written in English with long-term outcome data. The US Public Health grading system was used to grade evidence and rate the strength of conclusions. When evidence was insufficient, conclusions were based on expert opinion.CONSENSUS PROCESS. Participants were put into working groups with assigned topics and specific questions. Written materials were prepared and distributed before the conference, revised on the basis of input during the meeting, and presented to the full assembly for final review. If consensus could not be reached, conclusions were based on majority vote. All participants approved the final statement.CONCLUSIONS. The efficacy of gonadotropin-releasing hormone analogs in increasing adult height is undisputed only in early-onset (girls &lt;6 years old) central precocious puberty. Other key areas, such as the psychosocial effects of central precocious puberty and their alteration by gonadotropin-releasing hormone analogs, need additional study. Few controlled prospective studies have been performed with gonadotropin-releasing hormone analogs in children, and many conclusions rely in part on collective expert opinion. The conference did not endorse commonly voiced concerns regarding the use of gonadotropin-releasing hormone analogs, such as promotion of weight gain or long-term diminution of bone mineral density. Use of gonadotropin-releasing hormone analogs for conditions other than central precocious puberty requires additional investigation and cannot be suggested routinely.

47,XYY syndrome: clinical phenotype and timing of ascertainment

The Journal of pediatrics · 2013

📚 129 citations🎯 RCR 4.67Top 9% NIH

Effect of ascertainment and genetic features on the phenotype of Klinefelter syndrome

The Journal of pediatrics · 2008

📚 74 citations🎯 RCR 2.63Top 19% NIH🔓 Open Access

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Publications scientifiques (23) — classées par pathologie

Transversal16

Pédiatrie4

Pharmacovigilance2

Case report / série1

Essai clinique1

Génétique1

Recommandations1

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