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MME Daniele DE GUEYER

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Auteur de référence en rhumatologie
26 articles scientifiques publiés — un praticien à la pointe de la recherche

Rhumatologue

RPPS 10001192920

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Top publications · les plus citées

Sevabertinib in Advanced HER2-Mutant Non-Small-Cell Lung Cancer

The New England journal of medicine · 2025

📚 19 citations🎯 RCR 6.05🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Atezolizumab plus bevacizumab as first-line treatment of unresectable hepatocellular carcinoma: interim analysis results from the phase IIIb AMETHISTA trial

ESMO open · 2025

📚 14 citations🎯 RCR 4.55🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Targeting oral frailty indicators of late-life cognitive disorders and depression: a systematic review

Age and ageing · 2025

📚 13 citations🎯 RCR 6.30

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Abstract Background Oral frailty is an age-related gradual loss of oral function together with a cognitive and physical function decline. Previous systematic reviews and meta-analyses examined the association of some oral frailty indicators with late-life cognitive and late-life depression (LLD). However, none of these studies investigated a large series of possible indicators and outcomes. Objective To clarify the impact of oral frailty indicators on late-life cognitive disorders and LLD. Design Systematic review. Subjects Sixty-three studies (56,520,662 subjects) with 11 oral frailty indicators in four categories: (i) oral health status deterioration, (ii) decline in oral motor skills, (iii) chewing, swallowing, and saliva disorders, and (iv) oral pain. Methods From database inception to April 24, 2024, six different electronic databases were consulted by two independent researchers assessing the eligibility of 24,045 records against the inclusion criteria and found 63 studies fitting the eligibility requirements. The protocol was registered a priori with PROSPERO (CRD42021249428). Results Four oral frailty indicators (number of remaining teeth, periodontal disease, difficulties in chewing, and difficulties in swallowing) were associated with late-life cognitive impairment/decline, mild cognitive impairment (MCI), dementia, and LLD. Among categories, oral health status deterioration and chewing, swallowing, and saliva disorders were associated with late-life cognitive impairment/decline, MCI, dementia, and LLD. Decline in oral motor skills was associated with late-life cognitive impairment/decline, while oral pain was related only to LLD. Conclusion Certain oral frailty indicators may contribute to the development of late-life cognitive disorders and LLD.

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MME Daniele DE GUEYER

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Publications scientifiques (26) — classées par pathologie

Transversal14

Essai clinique2

Revue générale2

Santé mentale / fatigue2

Vraie vie / RWE2

Anti-IL-171

Anti-IL-231

Biomarqueurs / Auto-Ac1

Case report / série1

Économie santé1

Génétique1

IA en rhumatologie1

Pharmacovigilance1

Recommandations1

Revue / méta-analyse1

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